easymountmarxps - Crystallization Plate Scanner

  • marxps: crystallization plate evaluation made easy

    marxps crystal plate scanner

  • mar xps: close-up

    marxps crystal plate scanner

  • marxps: view towards beam

    marxps crystal plate scanner

  • marxps: fully integrated into mardtb control system

    marxps crystal plate scanner

  • marxps: perfect match with EIGER 4M detector

    marxps crystal plate scanner

  • marxps: intuitive graphical user interface for easy screening

    marxps crystal plate scanner

Overview:

The marxps crystallization plate scanner is a brand-new addition to our legendary mardtb  goniostat system.  Essentially, it is a translation stage for widely used crystallization plates, with horizontal and vertical movements controlled by the mardtb electronics. It allows for quick and easy screening of your crystallization trials and saves you from the pain and risk of taking crystals out of their trays. 

Highlights:

Modular: The  marxps is a modular component of our mardtb  goniostat. It can be added to existing mardtb goniostats or it can be purchased together with a new mardtb. As such, it can be combined with any X-ray source from Mo sealed tubes to latest synchrotrons and takes advantage of the unique features of the mardtb system like the automatic beam search and optimization.
Full integration: The marxps is fully integrated into the electronics control system of the mardtb  and does not require addtional electronical components.
Any detector: The marxps can be used with any supported X-ray detector: the mar345  image plate, the EIGER and PILATUS3 detectors by DECTRIS and the SX-165/MX-225 CCD-detectors by Rayonix. Support for other detectors available on request.
Normal and low profile plates: The system currently supports 96-well plates with 1 to 4 drops per well (e.g. Greiner and Swissci). Adapters for other types of plates available on request.
Crystal camera: The crystal camera of the mardtb  is focussed at the position of the drops of the crystallization plate. The video stream is available to the controlling computer.
Point & click centering: The crystal in the drop can easily be centered from the software by point-and-click using the computer mouse.
Sophisticated software: The mardtb software comes with full support of the marxps component to make plate screening really easy. The software allows for automatic data collection of prescreened drops as well as fully automatic screening using a defined grid. The crystal camera is used to shoot photos from the drops used for data collection so there is a perfect feedback about the success of your crystallization work.
Mobile control: Naturally, also the functions of the marxps system are supported by the brand-new mardtb app available for Android Please look at the mardtb app page for more details.
Affordable: The marxps system offers a very affordable possibilty to further enhance your mardtb goniostat system. Please ask for a quotation!

Principle of Operation:

Mount/unmount crystallization tray:
Take your crystallization plate and just insert it into the holding area. No screws or tools involved - just slide it in! The flexible steel bracket safely holds the tray in the appropiate place.
Fast horizontal and vertical translations:
The horizontal and vertical movements are implemented with stepper motors with a resolution of about 1 micron/step and speeds of about 2.5 mm/sec. Moving from well to well is done in 2-3 seconds.
Automatic data collection:
Data collection is carried in multiple ways. You may want to visually screen the plate first and select a series of drops to be used for actually collect data. Or you can be lazy and just make an automatic data collection based on a definable grid. Or you can just stay at the experiment and do exposures drop by drop. Whatever suits you best...
 

Downloads and manuals:

Download the marxps product presentation and our movies and convince yourself how easy crystal mounting and retrieving can be.

Movies are in mp4 format and use the H.264 codec. All movies are full size with 640x360 pixels resolution.

EIGER 1M EIGER 4M mardtbEIGER HYBRID PHOTON COUNTING Detectors

  • EIGER R 4M on mardtb goniostat

    Eiger R 4M detector

  • EIGER R 4M: 2 x 4 modules, 155 x 163 mm active area, 2070 x 2167 pixels, 5 frames/second

    Eiger 4M detector

  • EIGER R 4M on mardtb goniostat, side view

    Eiger 4M detector

  • EIGER R 4M on mardtb goniostat at 2-theta 10 deg.

    Eiger 4M detector

  • EIGER R 4M on mardtb goniostat, front view

    Eiger 4M detector

  • EIGER R 4M on mardtb goniostat, top view

    Eiger 4M detector

  • EIGER R 4M on mardtb goniostat, close-up

    Eiger R 4M detector


EIGER R pixel detector Overview:

The EIGER is the latest masterpiece of DECTRIS AG. As the famous PILATUS3, it is a hybrid photon counting detector. It features a virtually continuous read-out system with virtually no dead-time (10 microseconds) and frame rates of 10Hz (EIGER R 1M) or 5Hz (EIGER R 4M), respectively. The main benefit as compared to the PILATUS3 detectors is the small pixelsize of only 75 microns (PILATUS3: 172 microns) and hence the larger amount of pixels as compared to a PILATUS3 detector of the same physical dimension. 

marXperts now also offers full support for the EIGER series of detectors with our mardtb goniostat. In fact, the EIGER detectors are the perfect fit for the mardtb and data collection is fully integrated into our well-known data collection software.

The key advantages of using a EIGER detector with the mardtb are as follows:

  • extremely short read-out time of 10 microseconds allows for fine φ-slicing
  • very small pixel size of only 75 microns
  • shutterless data collection
  • extremely high sensitivity
  • extremely low noise
  • high dynamic range (32 bits)
  • no point-spread due to direct conversion leading to small spots with better I/σ  
  • fast screening experiments

The extremely short read-out time paired with an excellent sensitivity makes the EIGER R series of detectors highly suitable for in-house data collection or crystal screening on home lab X-ray sources like Excillum Metaljet, the marYX2G X-ray data collection system or rotating anode generators. Thanks to the very short read-out time the usual way of collecting data with the EIGER detectors is to leave the shutter open until the end of data collection ("shutterless operation"). This reduces an instrument error factor and may be beneficial to the data quality.

mar4MUpgrade of  mar345dtb  to  EIGER R 4M (mar4M) or EIGER R 1M:

Existing mar345dtb detector sytems can easily be upgraded with an EIGER detector, i.e.  the mardtb can be used together with the EIGER R 4M or EIGER R 1M detector. Due to its larger detector surface that eliminates requirements for collecting multiple data sets at 2-theta offsets, the EIGER R 4M detector clearly is your first choice.  When  using the small EIGER R 1M detector, it is possible to mount the detector in front of the mar345 mar345smar345 detector. One can then easily take away the small EIGER detector and use the large mar345 image plate detector if there is a need for a large detector surface. For this special combination the range of movement of the distance translation stage of the mardtb goniostat is 22 to 150 mm for the EIGER R 1M detector and 120 to 425 mm for the mar345 detector.

Configurations:

mardtb desktop beamline with Eiger R 4M detector
mar345dtbThe EIGER R 4M or 1M detector is mounted on a mardtb goniostat. The mardtb  “desktop beamline” features a fully automatic beam alignment system and more than 10 motors including an “inverted PHI” assembly and a 2-theta stage. The system can be operated with any X-ray source (sealed tubes to synchrotrons).
marmuX2G Data Collection System marmot marmux2gmarYX2G: An EIGER R 4M or 1M detector with a mardtb goniostat in combination with a marµS microfocus generator. This system is the perfect choice, when cost-of-ownership and maintenance issues come into play. Despite of the low price, the system is highly suitable for fast screening experiments, but also for complete data collections of small crystals and other kinds of diffraction experiments.
Excillum MetalJet X-ray source MetalJet high end system: If you are aiming for the ultimate performance in the home lab, a combination of a MetalJet X-ray source with a EIGER R 4M detector and a mardtb goniostat is the very best you can obtain today. Excillum's patented MetalJet technology beats any other conventional X-ray source in terms of brilliance and is a true alternative to a synchrotron. Please contact us for further details!

Specifications for EIGER R series:

 

1M

4M

Number of detector modules 2 2 x 4
Max. frame rate [Hz]: 10 5
Active detector area [mm]: 77.2 x 79.9 155.2 x 162.5
Number of pixels: 1030 x 1065 2070 x 2167
Dead area [%]: 3.5 5.6
Pixel size [µm] 75 x 75
Dynamic range
32 bits
Outside dimensions (H x W x L) 114x 133 x 240 235 x 235 x 372
Weight [kg] 3.9 15
Cooling Water-cooled Water-cooled
Power consumption [W] 75 300

For a full list of specifications and further details about the EIGER series of detectors please consult the DECTRIS web site.


Application note:

An exiting experiment has been done with a mar4M system consisting of the EIGER R 4M detector and a mardtb goniostat. The setup has been used to collect  a complete data set of a large protein with 350 amino residues to high resolution (1.5 Ang.) in just 30 minutes with extraordinary quality. Please see the application note AN07Sep17 for further details.


Downloads and manuals:

mar200K mar300K mar1M PILATUS3 mardtbPILATUS3 Hybrid Photon Counting Detectors

  • PILATUS3 R 1M: 2 x 5 modules, 169 x 180 mm active area, 981 x 1043 pixels, 7 ms read-out time

    Pilatus3 1M detector

  • PILATUS3 R 1M on mardtb goniostat, side view

    Pilatus3 1M detector on mardtb

  • PILATUS3 R 1M on mardtb goniostat, side view

    Pilatus3 1M detector on mardtb

  • PILATUS3 R 200K-A: 2 modules, 84 x 70 mm active area, 487 x 407 pixels, 7 ms read-out time, air-cooled

    Pilatus3 200K-A detector

  • PILATUS3 R 200K-A on mardtb goniostat at 20 degrees in 2-theta

    Pilatus3 200K-A detector on mardtb

  • PILATUS3 R 200K-A on mardtb goniostat at 0 degrees in 2-theta

    Pilatus3 200K-A detector on mardtb

  • PILATUS3 R 200K-A on mardtb goniostat, front view

    Pilatus3 200K-A detector on mardtb


Overview:

Since its introduction the hybrid photon counting technology implemented in the detectors manufactured by DECTRIS AG, Switzerland, have become the leading technology for synchrotron applications in crystallography and other fields of X-ray diffraction. The PILATUS3 R series of detectors have been designed specifically for home lab use. Technically, they are identical to the synchrotron versions except for the limited frame rate of "only" 20 images/second and will satisfy most in-house demands.

marXperts now offers full support for the PILATUS3 series of detectors with our mardtb goniostat. In fact, the PILATUS3 detectors of any size fit nicely on the mardtb and data collection is fully integrated into our well-known data collection software.

The key advantages of using a PILATUS3 detector with the mardtb are as follows:

  • extremely short read-out time of 7 ms allows for fine φ-slicing
  • shutterless data collection
  • extremely high sensitivity
  • extremely low noise
  • high dynamic range (20 bits)
  • no point-spread due to direct conversion leading to small spots with better I/σ  
  • fast screening experiments

The short read-out time paired with an excellent sensitivity makes the PILATUS3 series of detectors highly suitable for in-house data collection or crystal screening on conventional X-ray sources like the marYX2G X-ray data collection system or rotating anode generators. Thanks to the very short read-out time the usual way of collecting data with the PILATUS3 detectors is to leave the shutter open until the end of data collection ("shutterless operation"). This reduces an instrument error factor and may be beneficial to the data quality.

mar345dtb mar200k mar1MUpgrade of  mar345dtb  to  mar200K / 300K / 1M:

Existing mar345dtb detector sytems can easily be upgraded with a PILATUS3 detector, i.e.  the mardtb can be used together with a PILATUS3 200K-A, 300K or 1M detector.  When  using the small PILATUS3 200K-A detector, it is possible to mount the detector in front of the mar345 mar345smar345 detector. One can then easily take away the small 200K detector and use the large mar345 image plate detector if there is a need for a large detector surface. The only drawback for this special combination is that the range of movement of the distance translation stage of the mardtb goniostat is somewhat restricted: 22 to 150 mm for the PILATUS3 200K-A detector and 120 to 425 mm for the mar345 detector.

Configurations:

mardtb desktop beamline with PILATUS3 R 1M detector mar345dtbmar200K/300K/1M: The PILATUS3 R 200K-A, 300K or 1M detector is mounted on a mardtb goniostat. The mardtb  “desktop beamline” features a fully automatic beam alignment system and more than 10 motors including an “inverted PHI” assembly and a 2-theta stage. The mar200K system is a complete data collection system that can be operated with any X-ray source (sealed tubes to synchrotrons), the most cost efficient combination being the marYX2G system.
marmuX2G Data Collection System marmot marmux2gmarYX2G: A PILATUS3 R 200K-A, 300K or 1M detector with a mardtb goniostat in combination with a marµS microfocus generator. This system is the perfect choice, when cost-of-ownership and maintenance issues come into play. Despite of the low price, the system is highly suitable for fast screening experiments, but also for complete data collections of small crystals and other kinds of diffraction experiments.
Excillum MetalJet X-ray source MetalJet high end system: If you are aiming at the ultimate performance in the home lab, a combination of a MetalJet X-ray source with a PILATUS3 R 1M detector and a mardtb goniostat is the very best you can obtain today. Excillum's patented MetalJet technology beats any other conventional X-ray source in terms of brilliance and is a true alternative to a synchrotron. Please contact us for further details!

Specifications for PILATUS3 R series:

 

200K-A

300K

1M

Number of detector modules 2 3 2 x 5
Read-out speed [msec] 7 7 7
Max. frame rate [Hz]: 20 20 5
Active detector area [mm]: 83.8 x 70.0 83.8 x 106.5 168.7 x 179.4
Number of pixels: 487 x 407 487 x 619 981 x 1043
Dead area [%]: 4.3 5.5 7.2
Pixel size [µm] 172 x 172
Dynamic range
1 : 1.048.576 (20 bits)
Outside dimensions (H x W x L) 156 x 155 x 284 158 x 193 x 262 265 x 286 x 455
Weight [kg] 5.4 7.5 25
Cooling Air-cooled Water-cooled Water-cooled
Power consumption [W] 30 30 165

For a full list of specifications and further details about the PILATUS3 series of detectors please consult the DECTRIS web site.


Application note:

An exiting experiment has been done with a marYX2G X-ray generator system consisting of a marYS X-ray source, a mardtb goniostat and a PILATUS3 R 200K-A detector. The setup has been used to quickly collect with a capillary mounted lysozyme crystal at room temperature. Four hours of data collection were sufficient for ab initio phasing with the SHELX package. Please see the application note AN12Mar15 for further information or download the pdf file.

Another experiment has been carried out with a PILATUS3 R 1M detector mounted, again on a  marYX2G X-ray data collection system. This time, a much smaller frozen lysozyme has been used for ab-initio structure solution in a similar way. Please download the pdf file mar.AN31Jul15.pdf for further information.


Downloads and manuals:

mar345 mar345smar345=  Fast Image Plate Detector

  • The fastest image plate detector ever built!

    mar345s fast image plate detector

     
    Read-out time for 180 mm diameter: 9 sec


    "Since upgrading to the mar345s we only use the new fast scan modes. Great improvement!"
    Dr. Ingo Korndörfer, Head of Crystallography, Crelux GmbH, Munich
     
  • mar345=   on   mardtb goniostat

    mar345 image plate detector on mardtb goniostat

  • mar345=   in action

    mar345 image plate detector in action

  • mar345=   :   top view of reading head

    top view of reading head

  • Detail of the mar345=   :   image plate motor

    mar345 image plate motor


Overview:

At the forefront of modern X-ray structure work, the mar345 Image Plate Detector System offers you the best choice for recording diffraction patterns of small molecules as well as protein crystals. Furthermore, it is a powerful tool for use in the fields of powder diffraction, texture analysis, small angle scattering, fiber and neutron diffraction. Since its introduction in early 1997 the impact in the scientific community has been extraordinary. Close to 420 instruments have been installed by beginning of 2014. They can be found at almost all synchrotrons around the world where they are used as work-horses for all kind of diffraction experiments. Likewise, they are very popular at both commercial and public research institutes. You won’t find an X-ray detector with a better price/performance ratio anywhere!


mar345 mar345sImprovements in the  mar345=  detector

Yes, we know that you actually want to see the diffraction pattern as soon as the exposure has finished. This is why we kept thinking on how to improve the already fast mar345 image plate detector. Now, the mar345 is not a pixel detector but we have a nice solution for quickly screening samples. We introduce a new ultra-fast 150 µm scan mode that reduces the typical read-out time plainly by a factor of 2 compared to the standard 150 µm scan mode. The data quality in the new fast scan modes is as good as the the one in the standard scan mode! 

Nine seconds (!!!) for a 180 diameter read-out: this is world record! And only 30 seconds for the full 345 mm diameter as well.

Do you really want to collect your data on a tiny pixel detector with very low redundancy and such a small detection surface? Do you really want to have to expose your crystals so much longer than necessary? Do you really think, a pixel detector is a fast data collection device if you don't call a synchrotron your own? Talk to us: we will happily explain the difference! Now, that is a really fast detector.

If you want to see more details, please have a look at the most recent application note "Comparison of the fast and fine read-out modes of the mar345s image plate detector".


mar345 mar345sUpgrade of  mar345  to  mar345:

Most of the existing mar345 detectors can be upgraded to a mar345 mar345smar345= . The upgrade consists in replacing the detector controller and installing new software. This is straightforward to do within 30 minutes time. No expert knowledge is required. So why don't you ask for a quotation today?


Highlights:

Speed Scan times range from as little as 9 seconds for an area of 180 mm diameter to 30 seconds for an area of 345 mm diameter when using the new fast scan modes.
Active area: Huge diameter of 345 mm
Dynamic range: Due to highly improved optics and electronics raw data can be sampled multiple times: each pixel in the output image consists of 2 digital data when using the 150 micron scan modes. This makes a dynamic range of real 17 bits, i.e. 1:131.071. 
Sensitivity: The image plate material itself is sensitive for a broad range of X-ray photon energies from down to 4 keV (3 Ang.) up to 100 keV (0.012 Ang.). This property allows the detector to be used for a large variety of applications - with a special Gd coating even for neutron diffraction.
Efficiency: The read-out system of the mar345s Image Plate Detector is unique in its use of a single high performance 85mW laser which delivers more than 0.8µJ/pixel at the plate. This ensures that an extremely high percentage (>95%) of trapped F-centers are transformed into photostimulated luminiscence.
Noise: Since there is no dark current or leakage current, the intrinsic noise of the system is <= 1 photon equivalent!
Design: All the detector needs is inside the scanner. The one and only connection to the outside world is an Ethernet cable to your computer. Could an Image Plate Detector be more compact?
Calibration: Before being shipped, the scanners are carefully calibrated in our lab. In the course of that process a correction table is generated that will remain valid for the lifetime of the scanner. During that entire process we strictly apply a no-compromises policy. This ensures that instruments go to the customer in perfect shape and thoroughly tested for all functions.
Dependability: After many years of heavy-duty operation at many synchrotrons and home labs we are confident to say: there is nothing around that compares to the reliability of the mar345 scanners.
Cost-of-ownership: The mar detectors and goniometers are renowned for its reliability. Due to this fact and due to excellent serviceability of our products, real costs of ownership of our instruments are far inferior to those of our competitors.
Free software: Easy-to-use and versatile. Plus state-of-the-art data processing software at no costs. Our software distribution policy really makes a difference!

Configurations:

mardtb desktop beamline with mar345 image plate detector mar345dtbmar345dtb: The mar345s detector is mounted on a mardtb goniostat. The mardtb  “desktop beamline” features a fully automatic beam alignment system and more than 10 motors including an “inverted PHI” assembly and a 2-theta stage. The mar345dtb system is a complete data collection system that can be operated with any X-ray source (sealed tubes to synchrotrons), the most cost efficient combination being the marYX2G system.
marmuX2G Data Collection System marmot marmux2gmarYX2G: A mar345s detector with a mardtb goniostat in combination with a marµS microfocus generator. This system is the perfect choice, when cost-of-ownership and maintenance issues come into play. Despite of the low price, the system is highly suitable for screening samples, but also for complete data collections of small crystals.
mar345 image plate detector Stand-alone: Due to its compact design, the scanner can easily be integrated into basically any X-ray data collection setup. The scanner electronics provides a TTL-signal for operating a shutter. It also provides a source of high voltage (for feeding ionization chambers) as well as steps for driving up to 3 stepper motors. Thus, by means of the  provided software, the scanner may control an entire experiment.

Specifications:

Plate Diameter 345 mm
Usable detector area 93.480 mm²
Diameter of scanned area Software selectable: 180, 240, 300 or 345mm
Pixel size  Software selectable, 3 variants available:
a) 150 µm fine and 150 µm fast
b) 100 µm fine and 150 µm fast
c) 100 µm fine and 150 µm fine
Sensitivity 1 X-ray photon per ADC-unit at 8 keV
Energy range: 4 keV to 100 keV X-ray photons
Intrinsic noise < 1 photon equivalent
Dynamic range
1 : 131.000 (17 bits)
Phosphor BaFBr:Eu2+
Communication interface Ethernet (RJ45), 10MB/s
Erase lamps 1 halogen lamp: R7S 11x118mm, 500W
2 halogen lamps: R7S 11x80mm, 250W
Lifetime: 2000 hours (approx 100.000 scans)
Outside dimensions (H x W x L) 515 mm * 398 mm * 350 mm
Weight 53 kg
Energy consumption approx. 1000 Watt
Electricity 120 / 240V (7.5 A)
Ambiental temperature 4 - 24 °
Maximum humidity: 70 %

 


Scan times:

The patented read-out system combines a constant movement of the scanning head (driving down from the edge to the center of the plate) with an accelerated rotation of the plate. The actual rotation speed is inverse proportional to the current distance of the collection system to the center of the plate. This unique procedure of spiral readout ensures constant pixel read-out times over a large area of the plate. The maximum rotational speed of the plate is 3800 rpm.

The mar345s detector can be ordered in 3 variants, each one with a combination of 2 different scan modes:

a) 150 µm fine and 150 µm fast

b) 100 µm fine and 150 µm fast

c) 100 µm fine and 150 µm fine (standard mar345 detector)

IP Diameter [mm]
180
240
300
345
Scan mode
Fine
Fine
Fast
Fine
Fine
Fast
Fine
Fine
Fast
Fine
Fine
Fast
Pixelsize [µm]
150
100
150
150
100
150
150
100
150
150
100
150
Scan time [sec]
26
34
9
39
53
15
56
77
23
68
108
30
Cycle time [sec]
34
42
27
48
62
34
66
87
43
80
108
53

  Computer requirements:
CPU Pentium Pro 200Mhz or better (Intel, AMD, etc.)
Memory (RAM) >= 512 MB
Disk space >= 20 GB
Video card: Support for 24-bit colors at >= 1280x1024 pixels
Network card: Dedicated >= 10 Mbit/s with IP-address 192.0.2.2
TV-card: Optional feature for mardtb goniometer (see below)
Supported OS: Linux: Ubuntu
On request: Mac OS X, other Linux flavours
Required OS components X-windows, X11-environment, openmotif libraries

 

  • All computer systems MUST be equipped with a dedicated Ethernet card set to address 192.0.2.2
  • At installation time computers are expected to be FULLY FUNCTIONAL.
  • For the mardtb desktop beamline a video frame grabber is strongly suggested. MarXperts only supports this feature on Linux. Recommended models: Hauppauge WinTV Express or Asus MyCinema P7131 (PCI version). Consult the web to see wether your selected card is supported on Linux.

Downloads and manuals:

We have gained worldwide reputation with our range of state-of-the-art X-ray data collection systems for crystallography and material research. In fact, “Mar” has become a synonym for high-performance X-ray detectors and goniostats, that are renowned of being “best of their kind”. Far beyond technical specs, the mar345 image plate detectors and the mardtb goniostats have become a legend for their reliability. We are proud to say, that they are truly “Made in Germany”.

X-ray Detectors:

mar345 / mar345s image plate detector
mar345= Image Plate Detector:
The world’s most highly acclaimed image plate detector, featuring a huge active area of 345 mm diameter, software selectable pixel sizes of 150 or 100 microns and an unbeatable cost/performance ratio. Popular in home labs as well as synchrotrons for protein and small molecule crystallography, powder diffraction, texture analyses and other material sciences. No other area detector data with higher quality!
In August 2014 we introduced the new model mar345 mar345smar345=. It keeps one standard fine read-out modes with either 150 or 100 µm pixel size. We then added 4 new ultra-fast read-out modes with 150 µm pixel size. The read-out times are now as short as 9 seconds - world record! The gain in speed has only neglibile loss in data quality and is therefore highly suitable for screening.
Did you know that you can upgrade your existing mar345 detector to the mar345s? Please ask for a quotation!
 

EIGER R pixel detector EIGER Hybrid Photon Counting Detectors:
With the EIGER R series of detectors we are proud to bring the ultimate Dectris technology to your home lab. The R series detectors come with a 10Hz frame rate and a small pixel size of only 75 microns. You have a choice between the 1M model with an active area of 77 x 80 mm and the 4M model with a size of 155x162 mm. Both fit nicely on the mardtb goniostat and can be combined with a generator to form a marYX2G data collection system.

PILATUS3 R pixel detector PILATUS3 Hybrid Photon Counting Detectors:
Leading technology pixel detectors for synchrotron (X/S series) or home laboratory (R series). The R series detectors come with a read-out time of only 7 ms and allow for very fast fast data collection. Depending on your budget, you can get a 200K detector with a size of 70x84 mm, a 300K detector (84x106 mm) or a 1M detector (169 x 179 mm). All of them fit nicely on the mardtb goniostat and can be combined with a generator to form a marYX2G data collection system.

Rayonix SX-165 single CCD detector Rayonix SX-165 Single CCD Detector:
High-performance single chip CCD detector for synchrotron or home laboratory. Ideal for crystallography, SAXS, X-ray diffraction, or imaging, the SX-165 features a round 165 mm diameter active area, high dynamic range and 1 sec read-out time. An optional frame-shift mode of data collection allows time-resolved studies on the order of milliseconds.

Rayonix HS-series mosaic CCD detector MX225-HS Rayonix HS Series CCD Detector:
The world’s fastest and most innovative large-area CCD X-ray detector for protein crystallography and other X-ray diffraction experiments. The HS series detectors come as single chip variants (SX) or with multiple chips (MX) with up to 25 tiles. The MX Series detectors offer seamlessly tiled arrays of fiber-optic coupled CCDs, with no inactive strips between them. Deep cooling, ultra-fast readout with up to 140 frames/sec, low noise, and high sensitivity.

Goniostats:

mardtb desktop beamline mardtb "desktop beamline":
The most advanced goniostat for computer-controlled data collection. A unique feature is its capability of aligning itself to the X-ray beam - just a single mouse click is enough! At least 14 motors take care of positioning the sample or the detector or the entire instrument. The mardtb is the perfect platform for use with either mar345 image plate, PILATUS3R 1M/300K/200K pixel detector, EIGER 1M/4M pixel detector, Rayonix SX-165 or MX-225 CCD detector not only on home sources but also on synchroton beamlines.

marxps crystallization plate scanner marxxps:
The marxps crystallization plate scanner is a brand-new addition to the mardtb goniostat system. It is a translation stage for commonly used crystallization plates, with horizontal and vertical movements controlled by the mardtb electronics. It allows for quick and easy screening of your crystallization trials and saves you from the pain and risk of taking crystals out of their trays.

mardtb app mardtbapp - mobile app
The mardtb goniostat can now be controlled by a mobile device (Android, iOS in preparation). Take advantage of this unique feature in the world of X-ray crystallography.

easymount goniostat easymount:
The easymount goniostat is an extended version of the mardtb "desktop beamline" featuring an automatic mount and retrieval mechanism for both comfortable and safe sample handling under cryogenic conditions. This is a very nice tool, in particular for high-throughput crystal screening.

marcsc cryogenic sample changer marcsc "cryogenic sample changer":
A compact, robust and rather inexpensive automated sample mounting, retrieval and storage system for the mardtb "desktop beamline". The instrument allows unattended data collection of 19 samples. An integrated bar-code reader keeps your crystals organized.

Complete Data Collection Systems:

metaljet complete data collection system metaljetmetaljet Data Collection System:
You want to go for the ultimate high performance in-house system? Then don't think any longer and take the latest innovation in X-ray generation technologies, the Excillum MetalJet generator based on a liquid gallium alloy anode. This generator makes a perfect match with a high performance DECTRIS EIGER 4M or PILATUS3 R 1M X-ray detector mounted on our mardtb "desktop beamline" goniostat. The system is completed with an Oxford Cryosystems  cryo-cooler including a  marLiN2 automatic liquid nitrogen refill system, a nice experimental table and an easy-to-use radiation enclosure.
marmux complete data collection system marmux marmux2g marmyx marmusmarYX2G Data Collection System:
Take a state-of-the-art micro-beam sealed tube generator with a specially designed high-performance optics, add a mardtb "desktop beamline" and a mar345= image plate detector to it plus a cryo-cooler, put it into a shiny cabinet and you are getting a truly powerful yet very affordable complete X-ray data collection system - just perfect for macro-molecular crystallography. No water and electrical installations required - it will fit anywhere in your lab. And: do forget about those maintenance budgets you are used to see elsewhere! Want a DECTRIS PILATUS3 or EIGER instead of the mar345? No problem, just ask for it. 

Accessories:

marLiN2 LN2 refill system marlin2marLiN2 Liquid Nitrogen Refill System:
The marLiN2 is a fully automatic LN2 (liquid nitrogen) refill system. It is based on a high precision electronic weighing scale, a magnetic valve and an intelligent and versatile controller that automatically tops up an unpressurized LN2 dewar (typically 60 liters) from a supply line, e.g. a pressurized large LN2 dewar of 150l content or more. The marLiN2 system is the perfect addition to an Oxford Cryosystems Cooler (600, 700, 800 series) or similar systems and can be retrofitted easily to existing systems.

marcam marcammarcam X-ray CCD camera:
The marcam is a CCD camera coupled to a screen that converts X-rays into visible light. It will display an image of the direct X-ray beam in 20 fold magnification on a TV monitor.

automarautomar Data Processing Suite

automar GUI automar is a revolutionary program package for processing single crystal diffraction data from proteins and small molecules. It comprises a full-featured GUI that supports all programs of the automar-suite. In addition, the integration and scaling programs of the CCP4-suite (ipmosflm), the XDS-suite and the HKL(R)-suite are supported. Suitable default parameters and menu driven choices are provided wherever possible. For difficult situations, expert settings are possible, too. The time and expertise required to process data is reduced to a minimum. Data processing has never been more straightforward. Look further down for downloads...

History:

Version Date Description
3.0 Aug 2015
Full support for latest XDS and MOSFLM package.
Full support for Pilatus data processing with marProcess, XDS and MOSFLM
Scaling program 'scala' from CCP4 suite replaced by aimless.
Program calls use bash instead of csh. Please call automar/automar.setup.sh from the .bashrc file! 

Highlights:

Implementation of powerful new algorithms in the indexing, data integration and data scaling programs.
Automatic parameter selection and update in the GUI - no typing required.
Graphical visualization of all program steps.
Autoindexing with extremely high success rates.
Data integration with a minimum of selectable parameters.
Quick and easy migration between several data integration packages: marProcess/marScale, mosflm/scala, xds/xscale and denzo/scalepack.
Standardized input and output files.
Highly suitable for inexperienced crystallographers due to well chosen defaults.

Program Steps:

Diffraction parameters common to all program packages are entered here, e.g. cell axes, goniometer parameters, wavelength,etc.
automar: input area for diffraction parameters Setup:
Diffraction parameters common to all program packages are entered here, e.g. cell axes, goniometer parameters, wavelength,etc.
automar:  peak selection for indexing Peak Search:
Choose spots for single crystal indexing of a from a single image, a range of consecutive images, or a series of non- consecutive images. The spot list is editable. Spots can be manually added or deleted by point and click. The program discriminates alpha1/alpha2-splitting when using Mo-radiation.
automar: tabular listing of indexing results Indexing:
Unless there is a real problem with the crystal, the indexing program is going to index your diffraction pattern. As few as 20 reflection can be suffificient. The GUI presents an easily readable listing of cell and quality parameters for all 14 Bravais lattice types. If no space group has been supplied, the most likely one is picked. Indexing is very tolerant against errors in the beam center and the detector-to-crystal distance.
The indexing results can be fed directly into data integration programs marProcess, ipmosflm, xds or denzo. All refined parameters are loaded automatically into the GUI.
automar: t overview of the best data collection strategies Strategy:
The pogram finds the most suitable staring angle for a data collection. The quickest way of obtaining a complete data set is presented at one glance.
automar: automatic determination of integration boxes Integration:
The data integration program marProcess implements the "seed-skewness-method" (Bolotovsky et al., J. of Applied Crystallography, 28, pp-95 (1995)) and combines it with traditional profile fitting. This technique works extremely well for both protein and small molecule data and reliefs users from having to determine integration box sizes manually. Spot sizes and diffraction parameters are adapted on-the-fly and make reprocessing obsolete.
automar: data analysis with R-factor plots, etc. Scaling:
Program marPost sums up partial reflections from the integration step. It also does a post-refinement of crystal orientation, mosaicity, divergence and cell parameters.
Program marScale merges and analyzes the integrated data. The most important results are displayed in the GGUI and allow for quick evaluation. A wide variety of 2D-plots are also available.
automar: format conversion tools Truncate/Convert:
After scaling, tools are offered to feed the intensity data into program "truncate" out of the CCP4-suite to convert them into structure factors. A variety of format conversion programs is also available to convert output of the automar suite or other supported program packages into files suitable for the CCP4-package, SHELX, CNS, etc.

Downloads and manuals:

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